The Semple Lab

We contributed preliminary analyses to the publication (Diez-Roux et al, 2011) of the freely accessible Eurexpress digital transcriptome atlas (http://www.eurexpress.org), of the E14.5 mouse embryo. Over 15,000 genes were annotated for hundreds of anatomical structures and regions, down to (almost) cellular level, allowing the identification of tissue-specific and tissue-overlapping gene networks. We illustrated the value of the Eurexpress atlas by finding novel coexpressed clusters of genes active in particular structures such as the developing eye.