The Semple Lab

Emily Chambers’ study of higher order chromatin structure is published in PLOS Comp Biol (Chambers et al, 2013). For the first time this manuscript describes the regions of the mammalian genome that appear to have diverged at the level of their chromatin structure, rather than at the level of the DNA sequence. Intriguingly some of the regions involved contain genes involved in the development of the mammalian body plan in embryogenesis.